Obsessive compulsive symptoms in Gilles de la Tourette syndrome and obsessive compulsive disorder

AbstractThere is a well-established overlap in phenomenology between anorexia nervosa and obsessive-compulsive disorder, and between obsessive-compulsive symptoms and Tourette syndrome (TS). Five cases of eating disorders in patients with obsessive-compulsive symptoms and TS are presented. The identification of four similar cases in the literature putatively marks a subset of eating disorders with a link to TS and to obsessive-compulsive symptomatology. This association may reflect a common underlying neurobiologic imbalance.

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Disturbed Monitoring and Response Inhibition in patients with Gilles De La Tourette Syndrome and Co-Morbid Obsessive Compulsive Disorder

Behavioural Neurology ◽

10.1155/2003/832906 ◽

2003 ◽

Vol 14 (1-2) ◽

pp. 29-37 ◽

Cited By ~ 45

Author(s):

Sandra Verena Müller ◽

Sönke Johannes ◽

Berdieke Wieringa ◽

Axel Weber ◽

Kirsten Müller-Vahl ◽

...

Keyword(s):

Executive Functions ◽

Obsessive Compulsive Disorder ◽

Tourette Syndrome ◽

Response Inhibition ◽

Error Detection ◽

Neuropsychological Tests ◽

Cognitive Domain ◽

Control Group ◽

Obsessive Compulsive ◽

Compulsive Disorder

Objective:Fronto-striatal dysfunction has been discussed as underlying symptoms of Tourette syndrome (TS) with co-morbid Obsessive Compulsive Disorder (OCD). This suggests possible impairments of executive functions in this disorder, which were therefore targeted in the present study.Results:A comprehensive series of neuropsychological tests examining attention, memory and executive functions was performed in a group of 14 TS/OCD in co-occurrence with OCD patients and a matched control group.Results:While attentional and memory mechanisms were not altered, TS/OCS patients showed deficits in executive functions predominately in the areas of response inhibition and action monitoring.Conclusions:These findings provide further evidence for a substantial impairment of the frontal-striatal-thalamic-frontal circuit. We propose that the deficits in monitoring, error detection and response inhibition constitute the major impairment of TS/OCD patients in the cognitive domain.

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Association of the CHRNA7 promoter variant −86T with Tourette syndrome and comorbid obsessive-compulsive disorder

Psychiatry Research ◽

10.1016/j.psychres.2014.06.032 ◽

2014 ◽

Vol 219 (3) ◽

pp. 710-711 ◽

Cited By ~ 1

Author(s):

Birgitte Bertelsen ◽

Linea Melchior ◽

Camilla Groth ◽

Nanette Mol Debes ◽

Liselotte Skov ◽

...

Keyword(s):

Obsessive Compulsive Disorder ◽

Tourette Syndrome ◽

Obsessive Compulsive ◽

Compulsive Disorder

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The treatment of magical ideation in two individuals with obsessive compulsive disorder

The Cognitive Behaviour Therapist ◽

10.1017/s1754470x10000140 ◽

2010 ◽

Vol 4 (1) ◽

pp. 16-29 ◽

Cited By ~ 2

Author(s):

Danielle A. Einstein ◽

Ross G. Menzies ◽

Tamsen St Clare ◽

Juliette Drobny ◽

Fjola Dogg Helgadottir

Keyword(s):

Obsessive Compulsive Disorder ◽

Video Clip ◽

Magical Thinking ◽

Behaviour Therapy ◽

Obsessive Compulsive ◽

Magical Ideation ◽

Obsessive Compulsive Symptoms ◽

Compulsive Disorder ◽

Mediating Role ◽

Pre Treatment

AbstractData collected from clinical populations indicate that magical ideation (MI) may play a causal or a mediating role in the expression of obsessive compulsive symptoms. If this is the case then when targeted in treatment, symptoms of obsessive compulsive disorder (OCD) should be altered. Two individuals diagnosed with OCD received a trial treatment targeting magical thinking. The intervention consisted of a series of procedures designed to undermine superstitious/MI without targeting obsessions or compulsions. The procedures involved critical analysis of the following material: (1) a free astrology offer; (2) a horoscope prediction exercise; (3) a description of four different cultural explanations of the origin of fire; (4) an instructive guide for Tarot card readers; (5) a report of a UFO sighting; (6) a video-clip describing a cult festival; (7) a description of a ‘hoax’ channeler and (8) a superstition exercise. Measures of obsessive compulsive symptoms, superstition, MI and thought–action fusion were administered pre-treatment, post-treatment and at 3 months’ follow-up. According to the twofold criterion of Jacobson et al. (Behaviour Therapy 1984, 15, 336–352), following treatment the patients were identified as being recovered on measures of magical and superstitious thinking and on the Padua Inventory.

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Brain-derived neurotrophic factor: A genetic risk factor for obsessive-compulsive disorder and Tourette syndrome?

Movement Disorders ◽

10.1002/mds.20849 ◽

2006 ◽

Vol 21 (6) ◽

pp. 881-883 ◽

Cited By ~ 16

Author(s):

Stefanie Klaffke ◽

Inke R. König ◽

Fritz Poustka ◽

Andreas Ziegler ◽

Johannes Hebebrand ◽

...

Keyword(s):

Risk Factor ◽

Obsessive Compulsive Disorder ◽

Tourette Syndrome ◽

Neurotrophic Factor ◽

Genetic Risk ◽

Brain Derived Neurotrophic Factor ◽

Genetic Risk Factor ◽

Obsessive Compulsive ◽

Compulsive Disorder

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Books and More: Tictionary: A Reference Guide to the World of Tourette Syndrome, Asperger Syndrome, Attention Deficit Hyperactivity Disorder and Obsessive Compulsive Disorder for Parents and Professionals

Intervention in School and Clinic ◽

10.1177/10534512030390020801 ◽

2003 ◽

Vol 39 (2) ◽

pp. 127-127

Author(s):

Chris K. Ormsbee ◽

Spencer Nolan

Keyword(s):

Attention Deficit Hyperactivity Disorder ◽

Asperger Syndrome ◽

Obsessive Compulsive Disorder ◽

Tourette Syndrome ◽

Attention Deficit ◽

Obsessive Compulsive ◽

Compulsive Disorder ◽

Reference Guide ◽

Hyperactivity Disorder ◽

The World

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Severity of Obsessive-Compulsive Symptoms is Related to Self-Directedness Character Trait in Obsessive-Compulsive Disorder

CNS Spectrums ◽

10.1017/s1092852900002789 ◽

2004 ◽

Vol 9 (8) ◽

pp. 607-612 ◽

Cited By ~ 17

Author(s):

Carlos Cruz-Fuentes ◽

Claudia Blas ◽

Laura Gonzalez ◽

Beatriz Camarena ◽

Humberto Nicolini

Keyword(s):

Obsessive Compulsive Disorder ◽

Rating Scales ◽

Character Trait ◽

Depression And Anxiety ◽

Temperament And Character Inventory ◽

Obsessive Compulsive ◽

Obsessive Compulsive Symptoms ◽

Compulsive Disorder ◽

Behavioral Features ◽

Character Inventory

ABSTRACT:Objective:The present study examined the psychobiological Temperament and Character model of personality on obsessive-compulsive disorder (OCD) patients, as well as the relation of temperament and/or character dimensions on the severity of obsessive-compubive symptoms.Methods:Fifty-four subjects diagnosed with OCD, were assessed with the Temperament and Character Inventory, the Yale-Brown Obsessive-Compulsive scale and the Hamilton Rating Scales for depression and anxiety.Results:Compared with controls, OCD subjects displayed increased harm avoidance and lower self-directedness and cooperativeness. Low self-directedness and high Hamilton depression scores were associated with increased severity of obsessive-compulsive symptoms.Conclusions:The Temperament and Character profile of OCD patients characterized in the present stud personality model and can be linked to some of their behavioral features. Furthermore, our data provides support of the influence that some personality traits may have on the severity of OCD symptoms.

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Poster #241 OBSESSIVE COMPULSIVE SYMPTOMS BUT NOT OBSESSIVE-COMPULSIVE DISORDER ARE RELATED TO LOWER QUALITY OF LIFE IN SCHIZOPHRENIA

Schizophrenia Research ◽

10.1016/s0920-9964(12)71073-3 ◽

2012 ◽

Vol 136 ◽

pp. S368

Author(s):

Alp Ucok ◽

Aysu Tihan ◽

Rasit Tukel

Keyword(s):

Quality Of Life ◽

Obsessive Compulsive Disorder ◽

Obsessive Compulsive ◽

Obsessive Compulsive Symptoms ◽

Compulsive Disorder

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Complex phonic tic and disinhibition in Tourette syndrome: case report

Arquivos de Neuro-Psiquiatria ◽

10.1590/s0004-282x2001000400019 ◽

2001 ◽

Vol 59 (3A) ◽

pp. 587-589 ◽

Cited By ~ 2

Author(s):

Débora Palmini Maia ◽

Francisco Cardoso

Keyword(s):

Breast Cancer ◽

Case Report ◽

Basal Ganglia ◽

Obsessive Compulsive Disorder ◽

Tourette Syndrome ◽

Limbic Cortex ◽

Obsessive Compulsive ◽

Compulsive Disorder ◽

Behavioral Abnormalities ◽

Motor Tics

Tourette syndrome (TS) is a neuropsychiatric disorder characterized by a combination of multiple motor tics and at least one phonic tic. TS patients often have associated behavioral abnormalities such as obsessive compulsive disorder, attention deficit and hyperactive disorder. Coprolalia, defined as emission of obscenities or swearing, is one type of complex vocal tic, present in 8% to 26% of patients. The pathophysiology of coprolalia and other complex phonic tics remains ill-defined. We report a patient whose complex phonic tic was characterized by repetitively saying "breast cancer" on seeing the son of aunt who suffered from this condition. The patient was unable to suppress the tic and did not meet criteria for obsessive compulsive disorder. The phenomenology herein described supports the theory that complex phonic tics result from disinhibition of the loop connecting the basal ganglia with the limbic cortex.

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